The Use of Transgenic Pigs in PRRSV ResearchTransgenic Pigs in PRRSV Research Dr. Randy Prather, University of Missouri, talks about the idea of genetic engineering of pigs for PRRSV resistance. Dr. Prather shows the approaches to the development of the SIGLEC1 pigs that uses Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) to make CRISPR Bacon. Dr. Prather says some in vitro resistance to PRRSv infection has been identified but that challenge studies need to be done.